How can I calculate the SED for a given substance?

NOAEl-project provides an excel template where is possible to calculate the SED value in two diffrerent ways.

In any case you need the dermal absorption value (expressed as % or as μg/cm²⁾ to calculate the SED; if this parameter is missing, a SED equal to 100 must be used.
In the first sheet the "Calculated relative dayly exposure" will be automatically filled after the user has selected the cosmetic category of interest (body lotion, shampoo ...). In order to calculate the SED, the user has to manually insert the concentration in the cosmetic product (this value must be a number between 0 and 100, where 100 corresponds to 100%) and the dermal absorption expressed as %.

In the second sheet of the same excel file, the user can calculate the SED only if the dermal absorption value (espressed as μg/cm²) is available; all the other values needed for calculation are automatically retrieved from the table on the right.